Trace level analysis plays a critical role in the pharmaceutical industry, especially since it is a requirement to work at trace level for multiple types of testing, such as testing for extractables and leachables (E&L), in order to identify harmful compounds present. It can be difficult to navigate this type of testing because of the varying definitions of ā€œtrace levelā€ in each industry, also making analytical method validation a challenging task.Ā 

This white paper will:

  • Provide an overview of trace level and its impact on different industries
  • Examine issues related to trace level testing
  • Offer solutions for trace method analysisĀ 
  • Review a case study that compares different analytical methods for analyzing a rubber stopper.

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